Wolstan & Goldberg
Eye Associates

TELO Medical Center
1st Floor, Ste 100
23600 Telo Ave
Torrance CA 90505

Phone: (310) 543-2611
Fax: (310) 543-2056

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To learn more about LASIK, surgery for cataracts, or other eye care services for Torrance, Palos Verdes, and the Beach Cities, fill out the form below.

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Corneal Collagen Cross-Linking (CXL)

Crosslinking is a technique that has been clinically tested since 1998 to treat patients with a disease called keratoconus. Patients with keratoconus suffer from corneas that are weak, thin and irregularly shaped which causes poor vision. Crosslinking (CXL) is now being performed for patients with keratoconus in almost 450 centers throughout the world. Wolstan & Goldberg Eye Associates will be among the first in the South Bay to offer this exciting and advanced treatment through a phase 2 clinical research trial in 2013.

How Keratoconus Changes Your Vision

Keratoconus changes someone’s vision in two different ways:

1. When the cornea gradually changes from a ball shape to a cone shape, the smooth surface becomes wavy. This phenomenon is known as ‘irregular astigmatism’.

2. The other way it changes vision is nearsightedness, which occurs as the front of the cornea expands. In this case, only objects up close can be seen clearly while anything far away will look blurry.

Symptoms of Keratoconus

We will be able to observe your symptoms during our extensive eye exam by one of our experienced doctors. However, there are various visible symptoms that you should be aware of, as they could be caused by keratoconus.That being said, be sure to mention any of the below during an exam.

These symptoms include:

In order for us to be sure that you have keratoconus, we will measure the shape of the cornea. There are several different ways this can be done.

How Corneal Collagen Cross-Linking Works

Normal corneas have crosslinks between its collagen fibers that keep it strong and able to retain normal shape. Keratoconus causes the crosslinks to become weak allowing the cornea to bulge outwards causing poor vision. CXL strengthens and adds crosslinks so that the cornea becomes stabilized which stops the progression of keratoconus and prevents further vision deterioration.

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Eye with Keratoconus


corneal-collagen imageThe figures above show the parallel corneal layers (white) and the collagen crosslinks (red) which are increased that prevent the cornea from bulging out, becoming steep and irregular.

How It’s Done:

Eye drops of vitamins (riboflavin) are instilled in your eye at two minute intervals for 20 minutes after the removal of the surface layer of the cornea of your eye. You'll be instructed to gaze into a blue ultraviolet light which activates the riboflavin while you are comfortably reclined for 5 minutes. After the treatment is complete the thickness of your cornea will be measured. The effect of this treatment will be evaluated over the course of 6 months.

After the procedure

Once the Crosslinking treatment has been completed, patients can expect to experience the following after the procedure.

Eye care is always important after any procedure. If you have any further questions or concerns about what to expect afterwards, please do not hesitate to contact us. We would be more than happy to address them.

The Benefits

Crosslinking for keratoconus can stabilize the disease, improve your vision and make daily life more enjoyable. Often times CXL can prevent the need for a corneal transplant and allows patients to wear contact lenses and/or glasses more comfortably. Some patients may become candidates for ICL (implantable contact lenses), Intacs (corneal implants), and Lasik after CXL is performed, furthering your vision correction. With crosslinking available, vision restoration is possible.

Other benefits include:

Do not hesitate to give us a call if you have any questions whatsoever; whether it be about the risks, or to see if you are a likely candidate.

Contact Us

Please contact our Clinical Research department if you are interested in participating in our CXL clinical trial at 310-602-5640 or at studies@wolstaneye.com .

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